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Results: 15
Reassessment of weak parent-of-origin expression bias shows it rarely exists outside of known imprinted regions.
Carol A Edwards, William MD Watkinson, Stephanie B Telerman, Lisa C Hulsmann, Russell S Hamilton, Anne C Ferguson-Smith
Apr 12, 2023
Exploring ways to respond to rising obesity and diabetes in the Caribbean using a system dynamics model.
Leonor Guariguata, Leandro Garcia, Natasha Sobers, Trevor S Ferguson, James Woodcock, T Alafia Samuels, Cornelia Guell, Nigel Unwin
Apr 17, 2023
Diabetes and obesity present a high and increasing burden of disease in the Caribbean that have failed to respond to prevention policies and interventions. These conditions are the result of a complex system of drivers and...
Published by: PLOS global public health
The Role of Faculty Development in Online Universities
Faculty development continues to be an important topic in online education. As online program and course offerings are growing and adopted in popularity with many traditional brick and mortar universities, it is causing many...
Published by: IGI Global
Improving the Quality of “The Internet of Things” Instruction in Technology Management, Cybersecurity, and Computer Science
Maurice Dawson, Ashley Courtney-Dattola, Sharon Burton, Calvin Nobles, Delores Springs, Darrell Burrell
Apr 01, 2020
Many universities require end of course evaluations for all courses taught as tool for academic accreditation purposes. The reality is that often many academic departments either do not do anything or have no idea what to do...
Published by: IGI Global
Fumarate induces vesicular release of mtDNA to drive innate immunity.
Vincent Zecchini, Vincent Paupe, Irene Herranz-Montoya, Joëlle Janssen, Inge MN Wortel, Jordan L Morris, Ashley Ferguson, Suvagata Roy Chowdury, Marc Segarra-Mondejar, Ana SH Costa, Gonçalo C Pereira, Laura Tronci, Timothy Young, Efterpi Nikitopoulou, Ming Yang, Dóra Bihary, Federico Caicci, Shun Nagashima, Alyson Speed, Kalliopi Bokea, Zara Baig, Shamith Samarajiwa, Maxine Tran, Thomas Mitchell, Mark Johnson, Julien Prudent, Christian Frezza
Apr 08, 2023
Mutations in fumarate hydratase (FH) cause hereditary leiomyomatosis and renal cell carcinoma1. Loss of FH in the kidney elicits several oncogenic signalling cascades through the accumulation of the oncometabolite fumarate2....
Primitive haematopoiesis in the human placenta gives rise to macrophages with epigenetically silenced HLA-DR.
Jake R Thomas, Anna Appios, Emily F Calderbank, Nagisa Yoshida, Xiaohui Zhao, Russell S Hamilton, Ashley Moffett, Andrew Sharkey, Elisa Laurenti, Courtney W Hanna, Naomi McGovern
Apr 17, 2023
The earliest macrophages are generated during embryonic development from erythro-myeloid progenitors (EMPs) via primitive haematopoiesis. Although this process is thought to be spatially restricted to the yolk sac in the mouse...
MACROPHAGES Placenta Animals Humans Mice HLA-DR Antigens Hematopoiesis Embryonic Development Pregnancy Female
Published by: Nature Communications
CEERS Key Paper. II. A First Look at the Resolved Host Properties of AGN at 3 < z < 5 with JWST
Dale D. Kocevski, Guillermo Barro, Elizabeth J. McGrath, Steven L. Finkelstein, Micaela B. Bagley, Henry C. Ferguson, Shardha Jogee, Guang Yang, Mark Dickinson, Nimish P. Hathi, Bren E. Backhaus, Eric F. Bell, Laura Bisigello, Véronique Buat, Denis Burgarella, Caitlin M. Casey, Nikko J. Cleri, M. C. Cooper, Luca Costantin, Darren Croton, Emanuele Daddi, Adriano Fontana, Seiji Fujimoto, Jonathan P. Gardner, Eric Gawiser, Mauro Giavalisco, Andrea Grazian, Norman A. Grogin, Yuchen Guo, Pablo Arrabal Haro, Michaela Hirschmann, Benne W. Holwerda, Marc Huertas-Company, Taylor A. Hutchison, Kartheik G. Iyer, Brenda Jones, Stéphanie Juneau, Jeyhan S. Kartaltepe, Lisa J. Kewley, Allison Kirkpatrick, Anton M. Koekemoer, Peter Kurczynski, Aurélien Le Bail, Arianna S. Long, Jennifer M. Lotz, Ray A. Lucas, Casey Papovich, Laura Pentericci, Pablo G. Pérez-González, Nor Pirzkal, Marc Rafelski, Swara Ravindranath, Rachel S. Somerville, Amber N. Straughn, Sandro Tacchella, Jonathan R. Trump, Stephen M. Wilkins, Stijn Wuyts, L. Y. Aaron Yung, Jorge A. Zavala
Apr 14, 2023
We report on the host properties of five X-ray-luminous active galactic nuclei (AGN) identified at 3 < z < 5 in the first epoch of imaging from the Cosmic Evolution Early Release Science Survey. Each galaxy has been imaged with...
Published by: The American Astronomical Society
Spatial multiomics map of trophoblast development in early pregnancy.
Anna Arutyunyan, Kenny Roberts, Kevin Troulé, Frederick C K Wong, Megan A Sheridan, Ilia Kats, Luz Garcia-Alonso, Britta Velten, Regina Hoo, Elias R Ruiz-Morales, Carmen Sancho-Serra, Jarrod Shilts, Louis-Francois Handfield, Luca Marconato, Elizabeth Tuck, Lucy Gardner, Cecilia Icoresi Mazzeo, Qian Li, Iva Kelava, Gavin J Wright, Elena Prigmore, Sarah A Teichmann, Omer Ali Bayraktar, Ashley Moffett, Oliver Stegle, Margherita Y Turco, Roser Vento-Tormo
Apr 17, 2023
The relationship between the human placenta-the extraembryonic organ made by the fetus, and the decidua-the mucosal layer of the uterus, is essential to nurture and protect the fetus during pregnancy. Extravillous trophoblast...
Myometrium Decidua Organoids Stem Cells Trophoblasts Placenta Humans Transcription Factors maternal-fetal relations Cell Communication Cell Differentiation Cell Movement Pregnancy Pregnancy Trimester First Female Single-Cell Analysis Transcriptome multiomics
Published by: Nature
CEERS Key Paper. III. The Diversity of Galaxy Structure and Morphology at z = 3–9 with JWST
Jeyhan S. Kartaltepe, Caitlin Rose, Brittany N. Vanderhoof, Elizabeth J. McGrath, Luca Costantin, Isabella G. Cox, L. Y. Aaron Yung, Dale D. Kocevski, Stijn Wuyts, Henry C. Ferguson, Micaela B. Bagley, Steven L. Finkelstein, Ricardo O. Amorín, Brett H. Andrews, Pablo Arrabal Haro, Bren E. Backhaus, Peter Behroozi, Laura Bisigello, Antonello Calabrò, Caitlin M. Casey, Rosemary T. Coogan, M. C. Cooper, Darren Croton, Alexander de la Vega, Mark Dickinson, Adriano Fontana, Maximilien Franco, Andrea Grazian, Norman A. Grogin, Nimish P. Hathi, Benne W. Holwerda, Marc Huertas-Company, Kartheik G. Iyer, Shardha Jogee, Intae Jung, Lisa J. Kewley, Allison Kirkpatrick, Anton M. Koekemoer, James Liu, Jennifer M. Lotz, Ray A. Lucas, Jeffrey A. Newman, Camilla Pacifici, Viraj Pandya, Casey Papovich, Laura Pentericci, Pablo G. Pérez-González, Jayse Petersen, Nor Pirzkal, Marc Rafelski, Swara Ravindranath, Raymond C. Simons, Gregory F. Snyder, Rachel S. Somerville, Elizabeth R. Stanway, Amber N. Straughn, Sandro Tacchella, Jonathan R. Trump, Jesús Vega-Ferrero, Stephen M. Wilkins, Guang Yang, Jorge A. Zavala
Apr 14, 2023
We present a comprehensive analysis of the evolution of the morphological and structural properties of a large sample of galaxies at z = 3–9 using early James Webb Space Telescope (JWST) CEERS NIRCam observations. Our sample...
Published by: The American Astronomical Society
p53 and ovarian carcinoma survival
Martin Köbel, Eun-Young Kang, Ashley Weir, Peter F Rambau, Cheng-Han Lee, Gregg S Nelson, Prafull Ghatage, Nicola S Meagher, Marjorie J Riggan, Jennifer Alsop, Michael S Anglesio, Matthias W Beckmann, Christiani Bisinotto, Michelle Boisen, Jessica Boros, Alison H Brand, Angela Brooks-Wilson, Michael E Carney, Penny Coulson, Madeleine Courtney-Brooks, Kara L Cushing-Haugen, Cezary Cybulski, Suha Deen, Mona A El-Bahrawy, Esther Elishaev, Ramona Erber, Sian Fereday, Anna Fischer, Simon A Gayther, Arantzazu Barquin-Garcia, Aleksandra Gentry-Maharaj, C Blake Gilks, Helena Gronwald, Marcel Grube, Paul R Harnett, Holly R Harris, Andreas D Hartkopf, Arndt Hartmann, Alexander Hein, Joy Hendley, Brenda Y Hernandez, Yajue Huang, Anna Jakubowska, Mercedes Jimenez-Linan, Michael E Jones, Catherine J Kennedy, Tomasz Kluz, Jennifer M Koziak, Jaime Lesnock, Jenny Lester, Jan Lubiński, Teri A Longacre, Maria Lycke, Constantina Mateoiu, Bryan M McCauley, Valerie McGuire, Britta Ney, Alexander Olawaiye, Sandra Orsulic, Ana Osorio, Luis Paz-Ares, Teresa Ramón Y Cajal, Joseph H Rothstein, Matthias Ruebner, Minouk J Schoemaker, Mitul Shah, Raghwa Sharma, Mark E Sherman, Yurii B Shvetsov, Naveena Singh, Helen Steed, Sarah J Storr, Aline Talhouk, Nadia Traficante, Chen Wang, Alice S Whittemore, Martin Widschwendter, Lynne R Wilkens, Stacey J Winham, Javier Benitez, Andrew Berchuck, David D Bowtell, Francisco J Candido Dos Reis, Ian Campbell, Linda S Cook, Anna DeFazio, Jennifer A Doherty, Peter A Fasching, Renée T Fortner, María J García, Marc T Goodman, Ellen L Goode, Jacek Gronwald, David G Huntsman, Beth Y Karlan, Linda E Kelemen, Stefan Kommoss, Nhu D Le, Stewart G Martin, Usha Menon, Francesmary Modugno, Paul DP Pharoah, Joellen M Schildkraut, Weiva Sieh, Annette Staebler, Karin Sundfeldt, Anthony J Swerdlow, Susan J Ramus, James D Brenton
Apr 17, 2023
p53 ovarian cancer Prognosis Clear cell TP53 High-grade Serous Carcinoma Endometrioid Humans Carcinoma Endometrioid Ovarian Neoplasms Female Tumor Suppressor Protein p53 Carcinoma Ovarian Epithelial
Published by: The journal of pathology. Clinical research